Mast cells
Immune system cells that release histamine and other mediators in response to HIT triggers.
Mast cells are a key part of the immune system. In the context of histamine intolerance, they can be activated by various triggers such as food, allergens or stress. Once activated, they release large amounts of histamine and other inflammatory substances, which contribute to the symptoms of HIT.
Related terms
The moment a mast cell empties its storage vesicles and releases histamine and other inflammatory substances into its surroundings. This can be triggered by an allergen, but also by medication, heat, or stress.
Substances that release histamine from cells, worsening the symptoms of HIT.
The inability of the body to properly break down histamine, which leads to its excessive accumulation and manifestations.
An independent non-profit organization (Schweizerische Interessengemeinschaft Histamin-Intoleranz) that specializes in research, education and support for people suffering from histamine intolerance (HIT) and related disorders of mast cell metabolism.
The amount of histamine the body can still break down without issues. It is not fixed and changes from day to day depending on health, medications, hormones, and stress.